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AI in Medicine

Artificial Intelligence has tremendous potential to advance clinical practice and the delivery of patient care. 

NEJM AI

NEJM AI

The April 2025 NEJM AI issue is now published. NEJM AI is a journal exploring cutting-edge research and applications of artificial intelligence in clinical medicine. Visit NEJM AI.

NEJM AI Grand Rounds Podcast

NEJM AI Grand Rounds Podcast

Hosted by Arjun (Raj) Manrai, Ph.D. and Andrew Beam, Ph.D., NEJM AI Grand Rounds features informal conversations with a variety of unique experts exploring the deep issues at the intersection of artificial intelligence, machine learning, and medicine.

  • Large Language Models and the Medical Record

    L.G. McCoy, A.K. Manrai, and A. Rodman

    Instead of facilitating communication and transparency, the insertion of LLM-generated text directly into the medical record risks diminishing the quality, efficiency, and humanity of health care.

  • Large numbers of patients are already using AI tools to obtain medical advice. Rigorous trials of these tools will be important. But what will they be measured against?

More on AI in Medicine

  • Fundamentals of Medical Ethics

    The Ethics of Relational AI

    I. Sim and C. Cassel

    The relational nature of large language models and other forms of generative artificial intelligence raises additional ethical questions for medicine, beyond the daunting ethics surrounding predictive AI.

  • Wearable Digital Health Technologies in Medicine

    Wearable Digital Health Technologies for Epilepsy

    E. Donner, O. Devinsky, and D. Friedman

    One third of people with epilepsy have seizures despite medical treatment. The authors examine wearable digital health devices that can detect seizures and how these devices can affect epilepsy care.

  • Wearable Digital Health Technologies in Medicine

    This article reviews the use of digital wearable technologies for monitoring of three common cardiovascular conditions: hypertension, heart failure, and atrial fibrillation.

  • There are various possible futures for regulation of artificial intelligence in the United States. The history of rules governing the treatment of human subjects could hold important insights.

  • AI and Medical Education

    A. Cooper and A. RodmanN Engl J Med 2023;389:385-387

    Artificial intelligence could have broad implications for medical education. Educators could lead the way when it comes to integrating this technology into clinical practice.

  • Using AI to Interpret Medical Images

    P. Rajpurkar and M.P. LungrenN Engl J Med 2023;388:1981-1990

    The authors examine the advantages and limitations of current clinical radiologic AI systems, new clinical workflows, and the potential effect of generative AI and large multimodal foundation models.

  • Artificial Intelligence in Medicine

    A.L. Beam and OthersN Engl J Med 2023;388:1220-1221

    The editors announce both a series of articles focusing on AI and machine learning in health care and the 2024 launch of a new journal, NEJM AI, a forum for evidence, resource sharing, and discussion of the possibilities and limitations of medical AI.

  • GPT-4, a General AI Chatbot for Medicine

    P. Lee, S. Bubeck, and J. PetroN Engl J Med 2023;388:1233-1239

    Chatbots are computer programs with which one can have a conversation. In this article, the authors describe how the GPT-4 chatbot, which has been given a general education, could affect the practice of medicine.

NEJM AI Event

NEJM AI Event

AI Without Borders: Transforming Global Health Care

April 9, 2025

12:00 PM – 1:15 PM ET

Register for the FREE event here.

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