Surgery
Among older patients undergoing TAVI, dapagliflozin led to a lower incidence of a composite of death from any cause or worsening of heart failure than standard care at 1 year.
In this trial involving 543 patients with stroke due to occlusion of medium or distal vessels, endovascular treatment within 24 hours after the onset of symptoms was not effective in improving functional outcome at 90 days.
This review considers enteral nutrition in the context of disease-related malnutrition, provides evidence for the use of enteral nutrition in hospitalized patients, and discusses practice considerations.
In a trial involving patients with ischemic stroke due to medium-vessel occlusion, thrombectomy within 12 hours did not lead to a better functional outcome and lower mortality at 90 days than usual care.
1-20 of 2520 results
- Neoadjuvant PD-1 blockade with dostarlimab led to organ preservation in a high proportion of patients with early-stage mismatch repair–deficient tumors, with no compromise of surgical options.
- An 80-year-old woman presented with a 3-day history of abdominal pain. Imaging revealed numerous small gallstones in the gallbladder and cystic duct, consistent with cholecystitis.
- A 56-year-old man was transferred to a burn center for management of pavement burns on his feet that had occurred during a heat wave.
- This review considers enteral nutrition in the context of disease-related malnutrition, provides evidence for the use of enteral nutrition in hospitalized patients, and discusses practice considerations.
- With the aging of the population, aortic stenosis affects a growing number of patients, with a prevalence of 12.4% among persons who are at least 75 years of age, among whom 3.4% have severe aortic stenosis.1 Aortic stenosis is generally well tolerated for a prolonged period of time,...
- In a trial involving patients with ischemic stroke due to medium-vessel occlusion, thrombectomy within 12 hours did not lead to a better functional outcome and lower mortality at 90 days than usual care.
- Few procedures have gone through a decade of practice-changing clinical trials as impressive as thrombectomy for stroke. Beginning in 2015 with multiple trials showing a benefit with thrombectomy in early large-vessel occlusion, followed by the extended-window trials in 2018 and then the large core trials in 2023, it seemed that...
- In this trial involving 543 patients with stroke due to occlusion of medium or distal vessels, endovascular treatment within 24 hours after the onset of symptoms was not effective in improving functional outcome at 90 days.
- When an insurer repeatedly denies coverage of cochlear implant surgery for an infant with profound sensorineural hearing loss, his physician struggles with the ramifications of breaking a sacred promise.
- Among older patients undergoing TAVI, dapagliflozin led to a lower incidence of a composite of death from any cause or worsening of heart failure than standard care at 1 year.
- A 59-year-old man with a history of metabolic dysfunction–associated steatotic liver disease had an enlarging liver mass. Biopsy showed hepatocellular carcinoma. Management decisions were made.
- A full-term baby boy was transferred to the NICU at 30 hours of age with abdominal distention and failure to pass meconium. An abdominal radiograph showed dilated loops of small intestine.
- The role of axillary surgery in the management of breast cancer has changed. Sentinel-lymph-node biopsy is used to identify nodal metastases, but recognition of the lack of therapeutic benefit of this approach, coupled with the emphasis on tumor biology for decisions about systemic therapy, has led to trials examining the...
- This randomized trial involving patients with clinically node-negative, T1 breast cancer showed that the omission of axillary surgery was noninferior to sentinel-lymph-node biopsy.
- Nonacute subdural hematoma is common among older persons. With an aging population and increasing use of antiplatelet and anticoagulant agents, subdural hematoma is projected to become the most common cranial neurosurgical disease by 2030.1 Standard treatments — including glucocorticoids and statins for milder cases, with the addition of...
- Among patients receiving surgical or nonsurgical standard treatment for chronic subdural hematoma, adjunctive middle meningeal artery embolization reduced the risk of treatment failure within 180 days.
- Antibody-mediated rejection is an important determinant of allograft survival. Our understanding of antibody-mediated rejection has increased dramatically since the era when only hyperacute antibody-mediated rejection was known. Subacute, acute, and slowly progressive antibody-mediated rejection were subsequently recognized. Many aspects regarding the diagnosis and grading of allograft rejection have been developed...
- A 62-year-old man was admitted because of postprandial abdominal pain and weight loss. Cirrhosis had reportedly been diagnosed 1 year earlier; imaging showed portal vein thrombosis. A diagnosis was made.
- Kidney-transplant microvascular inflammation has a varied clinical presentation. This study of more than 16,000 biopsy specimens supports the recognition of additional rejection phenotypes to standardize diagnostics.
- Tubal ectopic pregnancy can be life-threatening. Management strategies include surgical treatment (salpingectomy or salpingostomy), medical treatment (methotrexate), or, in selected cases, expectant management.