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Nutrition in Medicine

This review article series focuses on fundamental and emerging concepts in nutrition, from the basic “pharmacodynamics” of food to evolving understanding of the gut and immunity and the role of the microbiome in health and disease.

  • Micronutrients

    Micronutrients

    L.H. AllenN Engl J Med 2025;392:1006-1016

    One third of people worldwide have at least one micronutrient deficiency. National surveys provide cross-sectional data, but inferring causality between deficiency and disease is difficult.

    Micronutrients
  • Food and Nutrition Insecurity

    Food and Nutrition Insecurity

    D. GallegosN Engl J Med 2025;392:686-697

    This review addresses the dimensions and mechanisms of food and nutrition insecurity, as well as assessment, populations at highest risk, and health consequences across diverse contexts.

    Food and Nutrition Insecurity
  • The Physiology of Hunger

    The Physiology of Hunger

    A. FasanoN Engl J Med 2025;392:372-381

    This review describes basic and translational research on the complex physiological processes of hunger, which regulate feeding habits and are influenced by socioeconomic, cultural, and behavioral factors.

    The Physiology of Hunger
  • Malnutrition

    Malnutrition

    T. Cederholm and I. BosaeusN Engl J Med 2024;391:155-165

    Malnutrition occurs in up to 10% of community-dwelling older people and contributes to morbidity and mortality. The two main pathologic pathways are nutrient deprivation and inflammation-induced tissue catabolism with anorexia.

    Malnutrition
  • Diets

    Diets

    M. Yannakoulia and N. ScarmeasN Engl J Med 2024;390:2098-2106

    The ways in which particular variations in diet influence health and the course of disease remain largely undefined. The authors review the spectrum of types of diet and describe some attributes of the various types.

    Diets
  • Taste Physiology

    Taste Physiology

    J.M. EganN Engl J Med 2024;390:1699-1710

    Much of what we learned in school about how we taste is wrong. Progress in understanding how taste works is providing insights that may help in the management of obesity, diabetes, and other illnesses.

    Taste Physiology
  • Energy and Macronutrients across the Life Span

    Energy and Macronutrients across the Life Span

    S.B. Heymsfield and S.A. ShapsesN Engl J Med 2024;390:1299-1310

    Poor nutrition is a major risk factor for disease. In this first review in a new series on nutrition, the authors provide an overview of nutritional guidance, with a focus on energy and macronutrients.

    Energy and Macronutrients across the Life Span
  • The editors announce a new series focusing on fundamental and emerging concepts in nutrition, from the “pharmacodynamics” of food to the gut and immunity and the role of the gut microbiome in health and disease.